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Acute Lymphocytic Leukemia
In 2003-2007, leukemia cases soared in children 0-4 years old and then decreased until 30. Age- and gender-based incidence rates were standardized to the canadian National railway Interstitial lung disease population.
Leukemia is cancer that starts in bone marrow and blood stem cells. These cells make red blood cells that deliver oxygen and nutrients tissues throughout the body. They also produce white blood cells that fight infections, and platelets which stop bleeding and form a blood clot.
What is Acute Lymphoblastic Leukemia (ALL)?
The spongy tissue located inside bones, bone marrow is the source of all blood cells. Blood stem cells (immature blood cells) normally develop with time. The cells are then transferred from bone marrows to the bloodstream where they carry oxygen and other substances throughout the body. They stop bleeding and fight infection.
The bone marrow is producing too many white blood cells that are still in their embryos in people suffering from leukemia. These cells overtake normal blood cells, preventing them from carrying out their function. Adult acute lymphoblastic (ALL) leukemia mainly affects white blood cells called lymphocytes. However, it could also affect other types of blood cells.
ALL is a cancer that develops in the bone marrow but it can also spread to other regions of the body. It is a very aggressive type of cancer that is likely to worsen quickly if left untreated. ALL can affect children and adults of any age, however it is more prevalent in children.
The outlook for people with ALL is influenced by their age when diagnosed and how they react to the treatment. The earlier leukemia can be detected, canadian national Railway Interstitial lung disease the better chances of getting rid of it. Patients suffering from ALL are typically treated with chemotherapy. The use of radiation therapy and/or stem cell transplants are sometimes used. If the chemotherapy is very intense, it may be followed by a second chemotherapy treatment to prevent the leukemia from coming back.
Diagnosis
The first step in diagnosing leukemia is to examine the bone marrow and blood samples for leukemia cells. This includes the complete count (CBC) and differential, which measures how many red blood cells are in the blood sample.
The results of the test can aid in determining if there are too few immature cells in the blood. This is a sign that leukemia may be present. The test can also determine how the white blood cells function and if they're able fulfill their tasks. The doctor might also recommend an MRI scan, which utilizes radio waves and strong magnets instead of x-rays to make detailed pictures of the body. This may help identify lymph nodes that have enlarged, as well as other problems.
In certain instances, leukemia cells might extend to the area around the brain and spinal chord. Doctors perform a test referred to as an lumbar syringe perforation to determine if this is the case. After numbing the region, they insert a needle into the bones in the lower back, over the spine and into the space around the spinal cord in order to collect the fluid sample to test. This test can also be used to inject chemotherapy drugs into CSF to treat cancers that have developed into the brain or spinal cord.
Other tests, such as the CT or ultrasound, may be used to determine if your organs have grown. A chest x-ray is sometimes done to look for indications of lung diseases, like a mass or an infection.
Treatment
The bone marrow makes blood stem cells that mature into red blood cells which transport oxygen and other compounds to all tissues in the body, platelets that create blood clots to stop bleeding, and white blood cells that fight infection and disease. Leukemia affects the white and red cells of blood, so their number is lower than normal.
The initial treatment is typically chemotherapy (medicine) which kills leukemia cells found in the bone marrow or blood and puts the leukemia in remission. This is known as remission therapy.
The second phase of treatment is to remove any remaining leukemia cells that may be hiding in the body, which causes leukemia to return. This is known as post-remission treatment.
If the leukemia returns after treatment (recurs or relapses) It usually occurs in bone marrow and blood, but sometimes can also develop in the brain or spinal fluid. If this occurs, the doctor could give more intensive chemo.
The majority of patients with ALL achieve a complete remission after the first treatment. The chances of having a complete remission are contingent on the age of diagnosis as well as other factors, like how advanced the leukemia has become. The overall cure rate is approximately 40% for adults with ALL. This is more common for younger patients than for older ones.
Prognosis
In the first treatment stage (called the remission-induction treatment) High doses of chemotherapy are used to eliminate leukemia from the bone blood and marrow. This reduces the chance of the cancer returning or recurrence.
The next phase of treatment aims to prevent leukemia from spreading within the spinal cord, brain and central nervous system (CNS). This is a phase that includes medications known as anti-metabolites, chemotherapies, and radiation therapy for the brain. It is also important to keep the number of healthy blood cells in the body (red and white blood cells) as high as is possible, so that they can defend the body from infection and circulate oxygen throughout the body.
People who have a remission in which fewer than 5% of the bone marrow cells are blast cells and blood count is normal, they have a good prognosis. However, the longer it takes for people to achieve an end-of-life, the worse their prospects. Another important indicator for prognosis is the existence of a small amount of residual disease following treatment.
Railroad workers like machinists pipefitters and electricians are typically exposed to diesel exhaust since they work on track equipment, locomotives and yards in areas that are not ventilated. They also are exposed to other toxic substances that are used in their jobs including solvents, degreasers, lubricants, and fumes. This can lead occupational illnesses and diseases like mesothelioma and lung cancer.
In 2003-2007, leukemia cases soared in children 0-4 years old and then decreased until 30. Age- and gender-based incidence rates were standardized to the canadian National railway Interstitial lung disease population.
Leukemia is cancer that starts in bone marrow and blood stem cells. These cells make red blood cells that deliver oxygen and nutrients tissues throughout the body. They also produce white blood cells that fight infections, and platelets which stop bleeding and form a blood clot.
What is Acute Lymphoblastic Leukemia (ALL)?
The spongy tissue located inside bones, bone marrow is the source of all blood cells. Blood stem cells (immature blood cells) normally develop with time. The cells are then transferred from bone marrows to the bloodstream where they carry oxygen and other substances throughout the body. They stop bleeding and fight infection.
The bone marrow is producing too many white blood cells that are still in their embryos in people suffering from leukemia. These cells overtake normal blood cells, preventing them from carrying out their function. Adult acute lymphoblastic (ALL) leukemia mainly affects white blood cells called lymphocytes. However, it could also affect other types of blood cells.
ALL is a cancer that develops in the bone marrow but it can also spread to other regions of the body. It is a very aggressive type of cancer that is likely to worsen quickly if left untreated. ALL can affect children and adults of any age, however it is more prevalent in children.
The outlook for people with ALL is influenced by their age when diagnosed and how they react to the treatment. The earlier leukemia can be detected, canadian national Railway Interstitial lung disease the better chances of getting rid of it. Patients suffering from ALL are typically treated with chemotherapy. The use of radiation therapy and/or stem cell transplants are sometimes used. If the chemotherapy is very intense, it may be followed by a second chemotherapy treatment to prevent the leukemia from coming back.
Diagnosis
The first step in diagnosing leukemia is to examine the bone marrow and blood samples for leukemia cells. This includes the complete count (CBC) and differential, which measures how many red blood cells are in the blood sample.
The results of the test can aid in determining if there are too few immature cells in the blood. This is a sign that leukemia may be present. The test can also determine how the white blood cells function and if they're able fulfill their tasks. The doctor might also recommend an MRI scan, which utilizes radio waves and strong magnets instead of x-rays to make detailed pictures of the body. This may help identify lymph nodes that have enlarged, as well as other problems.
In certain instances, leukemia cells might extend to the area around the brain and spinal chord. Doctors perform a test referred to as an lumbar syringe perforation to determine if this is the case. After numbing the region, they insert a needle into the bones in the lower back, over the spine and into the space around the spinal cord in order to collect the fluid sample to test. This test can also be used to inject chemotherapy drugs into CSF to treat cancers that have developed into the brain or spinal cord.
Other tests, such as the CT or ultrasound, may be used to determine if your organs have grown. A chest x-ray is sometimes done to look for indications of lung diseases, like a mass or an infection.
Treatment
The bone marrow makes blood stem cells that mature into red blood cells which transport oxygen and other compounds to all tissues in the body, platelets that create blood clots to stop bleeding, and white blood cells that fight infection and disease. Leukemia affects the white and red cells of blood, so their number is lower than normal.
The initial treatment is typically chemotherapy (medicine) which kills leukemia cells found in the bone marrow or blood and puts the leukemia in remission. This is known as remission therapy.
The second phase of treatment is to remove any remaining leukemia cells that may be hiding in the body, which causes leukemia to return. This is known as post-remission treatment.
If the leukemia returns after treatment (recurs or relapses) It usually occurs in bone marrow and blood, but sometimes can also develop in the brain or spinal fluid. If this occurs, the doctor could give more intensive chemo.
The majority of patients with ALL achieve a complete remission after the first treatment. The chances of having a complete remission are contingent on the age of diagnosis as well as other factors, like how advanced the leukemia has become. The overall cure rate is approximately 40% for adults with ALL. This is more common for younger patients than for older ones.
Prognosis
In the first treatment stage (called the remission-induction treatment) High doses of chemotherapy are used to eliminate leukemia from the bone blood and marrow. This reduces the chance of the cancer returning or recurrence.
The next phase of treatment aims to prevent leukemia from spreading within the spinal cord, brain and central nervous system (CNS). This is a phase that includes medications known as anti-metabolites, chemotherapies, and radiation therapy for the brain. It is also important to keep the number of healthy blood cells in the body (red and white blood cells) as high as is possible, so that they can defend the body from infection and circulate oxygen throughout the body.
People who have a remission in which fewer than 5% of the bone marrow cells are blast cells and blood count is normal, they have a good prognosis. However, the longer it takes for people to achieve an end-of-life, the worse their prospects. Another important indicator for prognosis is the existence of a small amount of residual disease following treatment.
Railroad workers like machinists pipefitters and electricians are typically exposed to diesel exhaust since they work on track equipment, locomotives and yards in areas that are not ventilated. They also are exposed to other toxic substances that are used in their jobs including solvents, degreasers, lubricants, and fumes. This can lead occupational illnesses and diseases like mesothelioma and lung cancer.
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